Product Overview
Feel Like Your Best Self Again.
Selentra HP™, powered by FEM-936™, supports women’s mid-life health.* Selentra HP supports the biological foundation of the menopause transition, backed by research and formulated for what comes next.*
FEM-936™Hormone-FreeVegan30-Day Supply
Worldwide Tracked Delivery
Dispatched in 5–10 business days via reputable international express carriers.
Duties & Taxes Included
All UK and European customs duties, clearance fees, and import VAT are pre-paid and settled at checkout. No unexpected courier fees upon arrival.
Volume DiscountBuy 2 or more & save 5%Discount applied automatically at checkout.
Formula Highlights: Vegan Hormone-Free cGMP Manufacturing
Key Features
- Supports a healthy inflammatory response during menopause*
- Promotes skin health and connective tissue integrity*
- Supports a healthy gut*
- Helps maintain healthy bone density and structure*
The New Blueprint for Women’s Longevity
The menopause transition is long, complex, and different for every woman. Symptoms come and go and change over time. Hot flashes for one woman, disrupted sleep, or a shift in inflammatory balance for another. What's consistent is the underlying process: estrogen decline impacts gut barrier function, bone and immune health and hormonal regulation, long before symptoms make them visible.
Most approaches address symptoms one at a time as they appear. Selentra HP supports the underlying system: the gut-hormone-bone axis through which estrogen decline makes its widest impact. It's formulated with two clinically studied, patented ingredients built specifically for this transition. Selentra HP is hormone-free and appropriate whether or not you're using menopausal hormone therapy, so you don't have to choose between the two.
This is a critical inflection point where many women's health trajectory changes. The science is clear, the support is not: menopause is understudied, under-treated, and under-discussed, and most care addresses symptoms rather than root cause. We can change that by treating the underlying biology.
Technical Specifications
| Brand |
Calroy Health Sciences |
| Product |
Selentra HP™ |
| Featured Blend |
FEM-936™ with VMK223™ and OsteoCaf™ |
| Daily Use |
2 capsules, split morning and evening |
| Supply |
30 days per bottle |
The Science
Beyond Hormones. Beyond Symptoms.
Women are underserved during the menopausal transition. Too many formulas aim to manage symptoms one at a time, rather than addressing the systems underneath them. Selentra HP targets the biological system that governs hormonal regulation, inflammatory balance, and skeletal health simultaneously during this transition. It’s foundational support.
As hormones change during menopause, a self-reinforcing cycle emerges: estrogen decline affects gut barrier permeability, immune balance shifts, and hormone and bone health are impacted. Three systems, one cascade, one originating event.
The impacts aren’t contained in the gut. The whole body feels this change, and foundational support can make a difference.
The Research
Clinically Validated. Peer-Reviewed. Trusted by Experts.
Selentra HP is powered by two clinically studied, patented ingredients, each supported by published, peer-reviewed clinical studies conducted in peri- and postmenopausal women, the population this formula was designed for.
In a 12-week, randomized, placebo-controlled trial of women ages 40–55, VMK223 was associated with measurable reductions in key inflammatory markers, including CRP and IL-6, two standard measures of systemic inflammation. These findings are consistent with support for a healthy inflammatory response during menopause, alongside improvements in the secondary endocrine markers cortisol and DHEA.
A separate published trial in the same population found measurable improvements in skin hydration (+28%), elasticity (+27%), and wrinkle depth (−28%) over 12-weeks, outcomes researchers connect to the same gut-barrier and immune pathway.
In a one-year clinical study, postmenopausal women taking OsteoCaf at 600 mg daily, the same dose used in Selentra HP, maintained stable bone mineral density at the majority of measured sites.
Key Studies
Supplementation with Postbiotic from Bifidobacterium Breve BB091109 Improves Immune Markers and Endocrine Function in Healthy Females (Motei et al., 2023)
Oral Postbiotic (VMK223) Supplementation Is Associated with Improved Instrumental Skin Appearance Parameters in Healthy Women Aged 40–55 Years (Pipino et al., 2026)
A Clinical Study of a Standardized Extract of Leaves of Dalbergia sissoo in Postmenopausal Women (Meeta et al., 2019)
Ingredient Highlights
Thoughtfully Sourced, Quality Controlled, Vegan
Selentra HP™ is powered by FEM-936™, a new proprietary blend of two clinically studied, patented ingredients formulated to support this connected system.*
VMK223™
VMK223™ is a postbiotic, a newer class of gut-health ingredient that works differently from probiotics or prebiotics. Rather than introducing live bacteria, VMK223 delivers the beneficial compounds bacteria produce directly. Postbiotics don't depend on the microbiome to work, they deliver the benefits directly. VMK223 engages two key immune receptors: one that calms gut-driven immune responses, and one that strengthens the gut barrier itself.* That makes it predictable by design. Unlike probiotics, whose effects vary with each woman's existing microbiome, VMK223 works at the receptor level, so it behaves consistently regardless of a woman's individual gut makeup.
OsteoCaf™
OsteoCaf™ is a patented extract of Dalbergia sissoo (Indian rosewood). Bone is living tissue, constantly being broken down and rebuilt. OsteoCaf promotes bone-building activity during the menopausal transition. It does this without hormonal activity, making it appropriate for any woman regardless of her history with hormone therapy.
Quality Control
Every batch of Selentra HP is produced under Calroy's Total Quality System, with strict compliance to FDA-defined current Good Manufacturing Practices (cGMP). Batch and test records are maintained to ensure guaranteed purity, potency, and quality.
These highlights are not a complete Supplement Facts panel. Refer to the bottle label for the full ingredient list and allergen information.
Dosage & Usage Guide
| When |
Directions |
| Morning |
Take 1 capsule. |
| Evening |
Take 1 capsule. |
Take 2 capsules daily. Splitting the dose supports consistent biological signaling throughout the day. Can be taken with or without food.
Each bottle provides a 30-day supply.
Backed by Calroy's 45-day, 100% money-back guarantee.
Before Use
Always consult your healthcare provider if you have medical conditions or take prescription medications.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
