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✦ AI Overview

MegaSporeBiotic™ (60 Capsules) by Microbiome Labs is a 100% spore-based, broad-spectrum probiotic clinically shown to maintain healthy gut barrier function, optimize immune health, and recondition the gut microbiome. Its unique blend of 5 dormant Bacillus spores delivers 4 Billion CFU with 99.99% digestive survivability — reaching the large intestine fully intact to colonize and increase microbial diversity. 60 capsules, 30-day supply at 2 capsules per day.

🧬 5-Strain Spore Formula 💪 4 Billion CFU 🧠 Gut Reconditioning ✅ No Refrigeration Required
🌍 Worldwide Delivery in 5–10 Days✅ Duties & Taxes PrepaidNo extra charges at delivery — what you pay at checkout is all you pay.
🏷️ Volume DiscountBuy 2 or more & save 5%Discount applied automatically at checkout.
✓ Dairy Free ✓ Gluten Free ✓ Soy Free ✓ Non-GMO ✓ Corn Free ✓ Preservative Free

Key Features

  • 100% Spore-Based, 5-Strain Formula — 295 mg / 4 Billion CFU Proprietary Spore Blend: B. licheniformis (SL-307), B. indicus HU36™, B. subtilis HU58™, B. clausii (SC-109), B. coagulans (SC-208).
  • 99.99% Digestive Survivability — Bi-phasic Bacillus life cycle allows spores to remain dormant through stomach acid and activate directly in the large intestine.
  • Reconditions the Gut — Actively promotes beneficial commensal bacteria colonization rather than simply passing through the digestive tract.
  • Immune & Barrier Support — Clinically shown to support healthy intestinal permeability (gut barrier function) and protective immune responses.
  • 60 Capsules — 30-Day Supply — 2 capsules per day; 100% shelf-stable, no refrigeration required.

Product Overview

MegaSporeBiotic™ is a 100% spore-based, broad-spectrum probiotic shown to maintain healthy gut barrier function. This unique all-spore formula effectively reconditions the gut by promoting microbial diversity and maintaining key health-promoting, commensal gut bacteria. Unlike conventional probiotics, MegaSporeBiotic’s Bacillus spores survive the entire digestive journey with 99.99% viability — no refrigeration required.

Each serving delivers 4 Billion CFU across 5 clinically studied Bacillus strains, each with distinct mechanisms: carotenoid antioxidant production (HU36™), intestinal barrier support and antimicrobial peptides (HU58™), immune equilibrium (SC-109), digestive comfort (SC-208), and B vitamin and enzyme production (SL-307).

Technical Specifications

Brand / Vendor Microbiome Labs
Category Probiotics / Gut Health
Probiotic Strains B. licheniformis (SL-307), B. indicus HU36™, B. subtilis HU58™, B. clausii (SC-109), B. coagulans (SC-208)
Potency Per Serving 4 Billion CFU (295 mg Proprietary Spore Blend)
Capsule Count 60 Capsules
Serving Size 2 Capsules Daily
Supply Duration 30-Day Supply
Refrigeration Required No — shelf stable (5-year shelf life)
Certifications Gluten Free, Non-GMO, Dairy-Free, Soy-Free, Corn-Free

Supplement Facts

Serving Size: 2 CapsulesServings Per Container: 30
Amount Per Serving % Daily Value
Proprietary Spore Blend
4 Billion CFU 		295 mg   †
Bacillus licheniformis (SL-307) †
Bacillus indicus HU36™ †
Bacillus subtilis HU58™ †
Bacillus clausii (SC-109) †
Bacillus coagulans (SC-208) †

† Daily values not established.

Other Ingredients: Cellulose, vegetable capsule (cellulose and water).
Always verify full ingredient listings on physical product label upon receipt.

📊 Dosage & Usage Guide

Always follow label directions. Consult your healthcare practitioner before use if pregnant, nursing, or taking prescription medications.

Demographic Recommended Dose Frequency & Directions
Adults (18+) 2 Capsules Take 2 capsules once daily with or without food, or as directed by your healthcare professional.
Children (Under 18) Consult Practitioner Consult your healthcare practitioner before use.

💡 How to Use

Directions: Take 2 capsules once daily with or without food, or as directed by your healthcare professional.

Caution & Warnings: As with any dietary supplement, consult your healthcare practitioner prior to use if pregnant, nursing, or taking prescription medications. Keep out of reach of children.

Frequently Asked Questions

What makes MegaSporeBiotic different from regular probiotics?

MegaSporeBiotic is a 100% spore-based probiotic, meaning all 5 strains exist in a protective endospore state that survives stomach acid, heat, and manufacturing with 99.99% viability. Conventional Lactobacillus and Bifidobacterium probiotics typically lose 99%+ of their potency before reaching the intestines. MegaSporeBiotic’s spores arrive fully intact in the large intestine where they germinate, colonize, and actively recondition the microbiome — rather than simply passing through.

Does MegaSporeBiotic need to be refrigerated?

No. MegaSporeBiotic is 100% shelf-stable with a 5-year shelf life and requires no refrigeration. The Bacillus spore form is inherently stable at room temperature, making it ideal for travel and everyday convenience. Store in a cool, dry place away from direct sunlight and heat.

Can MegaSporeBiotic be taken with food?

Yes — MegaSporeBiotic can be taken with or without food. Many practitioners recommend taking it with a meal to support the natural digestive process. It is compatible with most foods and beverages.

Can MegaSporeBiotic be taken alongside other Microbiome Labs products?

Yes. MegaSporeBiotic is the cornerstone of the Microbiome Labs protocol and is commonly used alongside MegaPreBiotic, Mega IgG2000, HU58, and RestorFlora. It is also generally compatible with most vitamins, minerals, and other dietary supplements. Consult your healthcare provider if you are taking prescription medications.

How long does it take to see results with MegaSporeBiotic?

Individual results vary. Many users report noticeable improvements in digestive comfort and regularity within 2–4 weeks of consistent use. Clinical studies on spore-based probiotics have shown measurable changes in microbiome composition within 30 days. For best results, use consistently as directed and consult your healthcare practitioner for personalized guidance.

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