Microbiome Labs HU58 Bacillus Subtilis Spore Probiotic 60 Capsules

Supplement Facts

† Daily values not established.

Caution & Warnings: As with any dietary supplement, consult your healthcare practitioner prior to use if pregnant, nursing, or taking prescription medications. Not recommended for children under 5. Keep out of reach of children.

What makes Bacillus subtilis HU58 different from regular probiotics?

Bacillus subtilis HU58 is a spore-forming probiotic, meaning it exists in a protective endospore state that allows it to survive harsh conditions — including stomach acid, heat, and manufacturing processes — that destroy most conventional Lactobacillus and Bifidobacterium strains. This gives HU58 100% survivability through the GI tract, ensuring the probiotic arrives fully viable in the intestines where it can colonize and exert its beneficial effects. It is also a naturally occurring soil-based organism with a long history of safe use and clinical study.

How does HU58 support gut health and digestion?

Once in the intestines, Bacillus subtilis HU58 supports gut health through several mechanisms: it promotes the production of key digestive enzymes including amylase (carbohydrate digestion), protease (protein digestion), and lipase (fat digestion); it helps maintain a balanced intestinal microflora by competing with less beneficial organisms; and it supports the gut-associated immune system. HU58 is also known to produce nattokinase and other beneficial compounds that support a healthy gut environment.

Can HU58 be taken with food, and does it need refrigeration?

Yes — HU58 can be taken with or without food. Because it is a spore-based probiotic, it does not require refrigeration and is stable at room temperature, making it ideal for travel and everyday convenience. Store in a cool, dry place away from direct sunlight and heat. The spore form also means it is not affected by hot beverages or cooking, though it is best mixed into cool or room-temperature foods if opening the capsule for children.

How does HU58 differ from RestorFlora, and when should I choose one over the other?

HU58 is a single-strain, high-concentration Bacillus subtilis HU58 formula designed for targeted, intensive gut and immune support — particularly useful during or after antibiotic use, periods of digestive stress, or as a focused daily probiotic. RestorFlora is a three-strain formula combining Saccharomyces boulardii, Bacillus subtilis HU58, and Bacillus clausii SC109, offering a broader-spectrum approach to intestinal flora balance. Many practitioners recommend HU58 for intensive gut reconditioning and RestorFlora for ongoing maintenance and travel support.

Is HU58 safe for children, and how should it be given to them?

HU58 is suitable for children ages 5 and up. For younger children who cannot swallow capsules, the capsule can be opened and the contents mixed into a cool or room-temperature food or beverage — such as applesauce, yogurt, or a smoothie. Do not mix into hot liquids. Always consult a pediatric healthcare practitioner before starting any new supplement for a child.

Can HU58 be taken alongside other Microbiome Labs products or other supplements?

Yes. HU58 is commonly used alongside other Microbiome Labs products such as MegaSporeBiotic, RestorFlora, and MegaPreBiotic as part of a comprehensive gut health protocol. It is also generally compatible with most vitamins, minerals, and other dietary supplements. If you are taking prescription medications — particularly immunosuppressants or antifungals — consult your healthcare provider before adding any probiotic to your regimen.