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SFI Health Berberine HCI 500mg by Klaire Labs delivers 500mg of berberine hydrochloride — the best-studied form — to support healthy lipid metabolism and metabolic function. Each 120-capsule bottle provides a 30–60 day supply, formulated to be hypoallergenic and free of the most common allergens. Trusted by healthcare practitioners since 1969.*

🌿 500mg Berberine HCI📉 Lipid Metabolism Support✅ Hypoallergenic🔬 Klaire Labs Formula💊 120 Capsules
🌍 Worldwide Delivery in 5–10 Days✅ Duties & Taxes PrepaidNo extra charges at delivery — what you pay at checkout is all you pay.
🏷️ Volume DiscountBuy 2 or more & save 5%Discount applied automatically at checkout.
Dietary & Allergen Info: Non-GMO Gluten-Free Dairy-Free Soy-Free Egg-Free No Artificial Additives

Key Features

  • 500mg Berberine Hydrochloride — The best-studied form of berberine, delivered at a clinically relevant dose per capsule.*
  • Lipid Metabolism Support — Studies show berberine exerts beneficial effects on lipid metabolism and cardiovascular markers.*
  • Hypoallergenic Formula — Free of milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and yeast.*
  • Practitioner-Trusted Since 1969 — Developed closely with physicians and intended for use under healthcare practitioner guidance.*
  • Flexible Dosing — 2 capsules, 1–2 times daily for a 30–60 day supply per bottle.
  • 120 Capsules — Extended supply for sustained metabolic support.

Berberine HCI 500mg by Klaire Labs (SFI Health) provides 500mg of berberine hydrochloride per capsule — the most bioavailable and researched form of berberine.* Studies with berberine demonstrate beneficial effects on lipid metabolism, making it a valuable tool for supporting cardiovascular and metabolic health.*

Formulated by Klaire Labs — trusted by healthcare practitioners since 1969 — this hypoallergenic formula is free of all major allergens and contains no artificial colors, flavors, or preservatives.*

Why Berberine Hydrochloride?

Berberine hydrochloride is the salt form of berberine most used in clinical research. Its standardized potency and absorption profile make it the preferred choice for practitioners seeking predictable, evidence-based results in supporting lipid and metabolic health.*

Technical Specifications

Product Form Capsules
Capsule Count 120 Capsules
Potency 500mg Berberine HCI per capsule
Active Ingredient Berberine Hydrochloride
Primary Support Lipid Metabolism, Metabolic & Cardiovascular Health
Serving Suggestion 2 capsules, 1–2 times daily
Supply Duration 30–60 Days
Net Weight 0.29 lbs
Allergen Statement Free of all major allergens; no artificial colors, flavors, or preservatives
Brand Klaire Labs / SFI Health

Supplement Facts

Serving size: 2 capsules

Servings per container: 60

Amount per serving% DV
Berberine HCI
(as berberine hydrochloride)
1,000mg   †

† Daily Value not established.

Other ingredients: Vegetable cellulose (capsule), microcrystalline cellulose, L-leucine, silica.

📊 Dosage & Usage Guide

Based on label directions. Consult your healthcare practitioner before use, especially if pregnant, nursing, or managing a health condition.

Demographic Dose Frequency Notes
Adults (18+) 2 capsules 1–2 times daily Take with food to improve tolerability. As directed by a healthcare practitioner.
Seniors (65+) 2 capsules Once daily Start with once daily and increase as directed. Monitor for GI sensitivity.
Pregnant / Nursing Not recommended Consult your OB/GYN or healthcare provider before use.
Children & Pediatric Not for children Not intended for use in children. Consult a licensed healthcare practitioner.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

💊 How to Use

  1. Take: 2 capsules, 1–2 times daily with 8 oz of water.
  2. Timing: Take with food to reduce potential GI sensitivity. Spreading doses throughout the day (e.g., with breakfast and dinner) may improve tolerability.
  3. Duration: Use as part of a structured protocol under healthcare practitioner guidance.
  4. Interactions: Berberine may interact with certain medications. Consult your healthcare practitioner if you are taking prescription drugs.
  5. Storage: Store in a cool, dry place away from direct sunlight. Keep out of reach of children.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Frequently Asked Questions

What is Berberine HCI and what does it do?

Berberine HCI is the hydrochloride salt form of berberine, an alkaloid found in several plants. Studies show it exerts beneficial effects on lipid metabolism and supports healthy metabolic and cardiovascular function.*

Why is the hydrochloride (HCI) form preferred?

Berberine hydrochloride is the most extensively studied form of berberine. Its salt form provides standardized potency and consistent absorption, making it the preferred choice in clinical research and practitioner protocols.*

Is this product safe to take with medications?

Berberine may interact with certain medications, including blood sugar and cholesterol medications. Always consult your healthcare practitioner before adding berberine to your regimen if you take prescription drugs.*

Is this product allergen-free?

Yes. This product is free of milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and yeast. It contains no artificial colors, flavors, or preservatives.*

Who makes this product?

This product is formulated by Klaire Labs, now operating under SFI Health. Klaire Labs has been trusted by healthcare practitioners since 1969 and develops products in close collaboration with physicians.*

All content on the website relating to products including (or are a similar nature to) medicines, vitamins and supplements are not intended to be used for the diagnosis, treatment, cure, or prevention of any health condition or disease. The information provided on this page does not constitute advice and should not be taken over the advice of medical practitioners, pharmacists, or any other licensed healthcare professionals. You should contact your healthcare provider in relation to this product if you believe you have a medical issue. Please ensure that you always read the label and follow any instructions that come with the product before you use or consume. Please do not rely on the information stated on our website.