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Pure Encapsulations CholestePure Plus II 120 caps

Original price $63.00 - Original price $63.00
Original price
$63.00 - $63.00
Current price $63.00

A unique blend of phytosterols, berberine and clinically studied bergamot extract to promote healthy lipid metabolism and overall cardiometabolic health*

Phytosterols are structural homologs of cholesterol that occur naturally in many plant foods. Over 30 years of research and 40 clinical trials suggest that phytosterols provide significant support for healthy lipid profiles. Well-established benefits of phytosterols on lipid balance stem primarily from the competition with cholesterol for occupancy in micelles, particles that carry cholesterol across the intestinal epithelium into the systemic circulation. Through this mechanism, phytosterols promote the excretion of cholesterol in the form of bile acids. Research indicates that the pine-derived phytosterols offered in this formula are comparable to phytosterols from other sources. Bergamot is a citrus fruit containing two newly discovered derivatives of the flavonoids hesperidin and naringenin. These compounds are naturally conjugated to a moiety known as hydroxymethylglutarate (HMG). In the liver, this unique molecule binds and modulates an enzyme known as HMG CoA reductase, which plays a central role in lipid biosynthesis. These unique compounds also target enzymes, transcription factors, and genes involved in lipid metabolism. In a study involving 192 volunteers, bergamot juice maintained healthy cholesterol levels in the normal range over a 30-day period. In a separate study of 80 subjects, 150 mg of flavonoids from Bergavit® 40 bergamot extract supported healthy lipid and glucose profiles over a 6-month period. Berberine supports cardiometabolic health through a variety of mechanisms, including support for glucose and lipid metabolism, antioxidant defenses, and cytokine production. In a randomized, placebo-controlled trial involving 116 subjects, berberine provided statistically significant support for glucose and lipid metabolism. It also helps maintain endothelial function by promoting healthy vascular cell adhesion molecule-1 (VCAM-1) expression and healthy iNOS activity.*

• Supports phytosterol intake and overall cardiovascular health*
• Promotes healthy cholesterol metabolism*
• Improved, soy-free formula
• Made with vegan ingredients

Serving Size:2 Vegetable Capsule
Servings Per Container:60

Amount Per Serving
Phytosterols (from PhytoPin® pine (Pinus pinaster) phytosterol complex)Amount Per Serving:500 mg
Berberine HClAmount Per Serving:400 mg
Bergavit® 40 bergamot (Citrus bergamia) extract (fruit) (standardized to contain 39% flavonoids)Amount Per Serving:160 mg
Other Ingredients:
Vegetarian capsule (cellulose, water)


We work to ensure that product information is correct; however, brands may make changes to products from time to time, and actual product packaging and materials may contain more and/or different information than that shown on our website. Please consult all labels, warnings, and directions prior to using or consuming products for the most accurate product information.

  • Gluten Free
  • Soy Free
  • Non-GMO
Recommendations: As a dietary supplement, take 2 capsules, 1-2 times daily, with meals.
Gluten-free, Soy-free, Non-GMO & Hypoallergenic
Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use. Keep out of the reach of children.
Store in a cool, dry place.

Customer Reviews

Based on 9 reviews
Seems to work well

I don't normally write reviews, but to let you all know my anecdotal experience. This dropped my LDL by 39 points in about a month. I also increased my fiber intake and cardio frequency for that time period.

Linda Jones
Watch product quantity

Product was half size for same price as previously ordered. Unhappy that quantity was not mentioned or viewable in online advertisement.

Peter Moyer
Works but hard on stomach.

This product did work. My blood glucose readings dropped around ten points shortly after taking. However after a week I had to stop. The product is hard on the stomach despite taking with food and it also caused constipation in my case as well. I would recommend drinking lots of water and eating more fiber with this product.

I. Mozes
It has no taste - unlike other products

Easy to swallow as has no taste

Formula has changed for the worsse

Since the formula was changed recently from liquid to powder the quality has deteriorated... Product causes heavy reflux for hours