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Pure Encapsulations KetoBrain Energy 10.6 oz

Original price $73.60 - Original price $73.60
Original price $73.60
$88.32 - $88.32
Current price $88.32

Offers a blend of ketogenic mineral compounds to support healthy brain function, weight management and athletic endurance*

Ketones are important respiratory fuel created from fatty acids and act as the main reserve fuel for the brain when glucose is low or in times of very high energy demand, such as a low-carbohydrate diet, prolonged exercise, or lactation. In fact, when ketones are abundant in the blood, such as during caloric restriction or a ketogenic diet, the brain can obtain up to 60% of its energy from their oxidation. This condition, known as nutritional ketosis, can be maintained for years, and is quite different from metabolic acidosis/pathological ketosis, which can arise in type I diabetes due to severe insulin deficiency. Ketones do cross the blood-brain barrier and have been shown to be neuroprotective, promoting oxidative defense, NAD+/NADH ratio, and enhancing mitochondrial respiration. In addition to acting as an energy source for the brain, ketones also support cerebral blood flow.

In a human intervention study involving 20 elderly subjects and young controls, administration of 30 g MCT to increase ketone concentration resulted in an increased overall brain energy metabolism by 3%, without altering brain glucose consumption. It has been shown in animals that ketone bodies can also replace glucose as a cellular signal in the central nervous system. Fasting in humans is associated with an increase in ketones. Conversely, administering ketones directly into the brain of rats results in body weight loss without changing food intake, nor affecting blood glucose levels or liver glycogen levels. Subcutaneous injections result in decreased food intake, specifically targeting a decrease in meal frequency and the time between meals.

In a randomized, controlled, crossover trial involving 15 healthy subjects, consumption of ketogenic esters after an overnight fast resulted in significantly decreased ghrelin, glucagon-like peptide 1 (GLP-1), and peptide tyrosine (PYY) compared to a dextrose control. Subjects also reported decreased hunger and desire to eat. Research studies involving athletes indicate that ketones also increase fat oxidation in the muscle during exercise, acting as an alternative fuel, even in the presence of carbohydrate and insulin. Additionally, they result in decreased plasma lactate concentrations, suggesting support for athletic endurance and muscle comfort.*

Provides weight management support as part of a healthy lifestyle with a reduced calorie diet and regular exercise.*

• Offers a blend of ketogenic mineral compounds to support healthy brain function, weight management and athletic endurance*
• Designed to be used in combination with a low-carbohydrate ketogenic diet and/or to support brain and muscle function*
• 10 grams of beta-hydroxybutyrate per serving
• Convenient, great tasting strawberry-lemonade powder formula for easy dispensing
• Made with hypoallergenic, vegan ingredients
Serving Size:2 Scoop
Servings Per Container:20

Amount Per Serving% Daily Value
CaloriesAmount Per Serving:5
Total CarbohydrateAmount Per Serving:1 g
Calcium (from calcium beta-hydroxybutyrate)Amount Per Serving:600 mgDaily Value:46%
Magnesium (from magnesium beta-hydroxybutyrate)Amount Per Serving:350 mgDaily Value:83%
Sodium (from sodium beta-hydroxybutyrate)Amount Per Serving:900 mgDaily Value:39%
Beta-Hydroxybutyrate (from a blend of calcium beta-hydroxybutyrate, magnesium beta-hydroxybutyrate, and sodium betahydroxybutyrate)Amount Per Serving:10 g
Other Ingredients:
citric acid, natural strawberry and lemonade flavors, malic acid, purified stevia leaf extract


We work to ensure that product information is correct; however, brands may make changes to products from time to time, and actual product packaging and materials may contain more and/or different information than that shown on our website. Please consult all labels, warnings, and directions prior to using or consuming products for the most accurate product information.

  • Gluten Free
  • Non-GMO

Recommendations: Add 1 serving to 8 oz. of water, milk or juice. Shake or stir until dissolved.

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Consume within 90 days after opening. Keep out of reach of children.

Use only if safety seal is intact. Packaged by weight, not volume. Settling may occur. Store in a cool, dry place.

Customer Reviews

Based on 6 reviews
I think it works

I actually felt it helped a lot with the brain fog!

Keto supplement

Doing a Keto diet. This is a good supplement. the flavor is a bit tart.

I LOVE this stuff.

I absolutely LOVE this stuff. The flavor is so good - it's like Sweet Tart candy! It's really helped to balance my electrolytes and bring down the swelling in my legs. I love this stuff and will have it every day for as long as they make it!

Didnt help

Its a great brand and we use their products. This particular one doesnt seem to provide benefits that it claims. At least after using it couple weeks we didnt see any changes.

Wonderful product

Wonderful product! I have it every morning.