In the Hopes that this review will help someone in a similar situation, I'm dealing with a grade 2 rectocile and constipation. As we knows, you have to find what works best for you, but I have found this to be an excellent addition once or twice a week. I reserve a laxative to emergancy situations only and amenable to manage pretty well with diet, magnesium, probiotic, and occasional stool softner. The hardest part for me is to not push. It makes everything worse. The cleansemore is probably my favorite. It is gentle, no pushing, and it never fails, I will actually go twice the following morning. Nothing makes me go twice and I have immediate relief. It really does cleanse and empty your bowels. I only take 1 pill and there are no stomach pains or any discomfort. It works within 8-12 hours for me