I have a standard poodle. I found he had a tick on him and pulled it (I I have many times before on our rabbit hounds on a farm). Tick located just behind shoulder and it wasn't like others I've pulled--the area was extremely inflamed. A week or so later, dog began displaying severe symptoms. Of course this is very difficult for dog and owner. In our case, the dog that rarely ever yelped would to so without reason... perhaps a sudden movement or other set it off. Dog can't speak English so don't know for sure. From my research, paired with tick bite and symptoms, seemed likely the cause. From rsearch, i found Ledum 1m is homeopathic medicine to treat my dog. I live in large city--couldn't find it local. Couldn't find it here. Paid some extra to "next day air" it. All I can say is once consumed by dog (don't recall dose, and am afraid to mislead anyone--this detail is easily found online though), his symptoms were greatly reduced. And the reduction happened withint 24h. In my experience, I'm confident it worked. I have taken this ledum 1m myself... I have given it to my dog--no sideeffects experienced. In hindsight, I'm quite confident that my dog had lyme. After this episode, I had my dog at vet for yearly checkup and vet asked about health.... I told him about this and all he said was "without a test, you don't know your dog had lyme." Ok... Found tick, dog reacted massively(relative to other ticks I've removed) to tick bite, 'lyme-like' symptoms (look them up) began within a month, he consumed ledum 1m... All negative gone. Totally worth trying--he's part of the family. I'd guess (shouldn't be allowed to guess, but yearly shots are $100) our vet would have charged $500! My dog was going through hell... yelping... he never did this before or after giving him ledum. I'm very convinced it worked. I hope it works for you too. I endorse this stuff... and I get nothing for it. Good luck!