I realllly wanted this product to work but I should have read the reviews first. ?? I noticed a positive difference from my second dose. I was more calm and focused at work. I work in customer service so I noticed right away that my thoughts weren't rushing and than my brain didn't go into panic mode whenever the phone rang. BUT, 4th day on the supplement and the itchiness started. Just horrible and unpleasant! On my arms, legs, back and the palms of my hands. How do your palms get itchy?? Seriously! I started thinking what I had eaten that I could be allergic to and the only culprit is this supplement. I looked into it and turns out I'm not the only one. Plus, now I'm worried ab liver damage. Although I don't think I took it long enough to cause any significant damage. I hope not. Now I'm scared to try a different brand. Alas...I will have to return to being my nervous, anxiety driven self! ??